What is 'aLeaves'?
allows you to collect homologs of
the sequence of your interest. Those sequences can be passed on to the
web server for sophisticated multiple alignment, and then to tree
building. This initial process one can perform here is just like
(termini of trees) from diverse a
This is why we designated this tool 'aLeaves
Start the search
(powered by NCBI Blast)
your "query" peptide
sequence in the fasta
database (one or more) (number
of sequences in parentheses):
1. Human -
2. Human - Ensembl (100,778)
3*. Non-human eutherians - Ensembl (818,207)
4. Non-eutherian mammals - Ensembl (83,640)
- Ensembl (558,533)
6. Cartilaginous fishes and cyclostomes (79,933)
*. All vertebrate
entries except mammalians in NCBI Protein (3,004,188)
8. Invertebrate deuterostomes (135,695)
9. Arthropods (620,800)
10. Nematodes (264,003)
11. Other protostomes (262,588)
metazoans (cnidarians, placozoan
& poriferan) (424,402)
entries except vertebrates in NCBI Protein (3,349,417)
(Caution: selecting the
database marked with * will largely slow down the search)
Number of homologs to collect:
number should not exceed 10000)
Set low complexity
filter or not
of NCBI Blast]:
Please confirm that the output of this search will later be transferred
to the MAFFT server at AIST for downstream processing.
Currently, searches are only executed in peptide databases using a
single peptide sequence as query with BLASTP.
To cite aLeaves
facilitates on-demand exploration of metazoan gene family trees on
MAFFT sequence alignment server with enhanced interactivity.
Christian M. Zmasek, Osamu Nishimura, and Kazutaka Katoh.
2013. 41 (W1): W22-W28.